Flyout hunting in Alaska for big game is the best way to assure some success in your hunt. The advantage to flyout hunting being that you're far from any road system, you're able to locate animals by air on the day preceding your hunt and able to choose an appropriate location for your hunting camp.
The majority of unguided flyout hunting expeditions, are flown on float equipped aircraft capable of landing in any of tens of thousand of lakes and rivers in the various ADF&G (Alaska Department of Fish & Game) Game Management units. The complete book of Alaska hunting regulations for 2008 - 2009 can be found here. Big game and bag limit regulations can be found here.
If you're not a resident of Alaska, there are certain restrictions or requirements regarding unguided big game hunts for non-residents. Be sure to familiarize yourself with these regs, before you book an expensive flyout hunting trip.
An Alaska flyout hunt is more likely to produce successful results than a hunt from the road system.